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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNA2 All Species: 27.27
Human Site: S245 Identified Species: 54.55
UniProt: P20248 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20248 NP_001228.1 432 48537 S245 Y I D R F L S S M S V L R G K
Chimpanzee Pan troglodytes XP_517420 432 48476 S245 Y I D R F L S S M S V L R G K
Rhesus Macaque Macaca mulatta XP_001100860 432 48504 S245 Y I D R F L S S M S V L R G K
Dog Lupus familis XP_540965 432 48633 S245 Y I D R F L S S M S V L R G K
Cat Felis silvestris
Mouse Mus musculus P51943 422 47265 S235 Y I D R F L S S M S V L R G K
Rat Rattus norvegicus Q6AY13 421 47676 C234 F L D R F L S C M S V L R G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513040 465 52108 S276 Y I D R F L S S M S V L R G K
Chicken Gallus gallus P43449 395 44062 M210 I D R F L S S M S V L R G K L
Frog Xenopus laevis P47827 415 46651 V230 R F L S S M S V L R G K L Q L
Zebra Danio Brachydanio rerio NP_694481 428 47894 S241 Y I D R F L S S M S V L R G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14785 491 56134 Q270 Y L D R F L S Q M A V V R S K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38819 450 50623 G256 L I D W F L H G N Y V Q R Q Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 91.4 N.A. 85.4 46.5 N.A. 69.2 63.4 57.6 58.7 N.A. 32.5 N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.3 95.3 N.A. 90.9 60.1 N.A. 76.9 72.2 70.3 69.9 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 100 6.6 6.6 100 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 13.3 20 100 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 9 84 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 9 0 9 84 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 9 0 9 67 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 9 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 75 % K
% Leu: 9 17 9 0 9 84 0 0 9 0 9 67 9 0 17 % L
% Met: 0 0 0 0 0 9 0 9 75 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 9 0 17 9 % Q
% Arg: 9 0 9 75 0 0 0 0 0 9 0 9 84 0 0 % R
% Ser: 0 0 0 9 9 9 92 59 9 67 0 0 0 9 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 9 84 9 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 67 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _